Dynamics of genetic and somatic trade-offs in ageing and mortality

Journal Citation

Arends D, Ashbrook DG, Roy S, Lu L, Sloan Z, Centeno AG, Lamour KH, de Magalhães JP, Prins P, Broman KW, Sen S, Mitchell SJ, MacArthur MR, Akin ÖA, Li X, Bajwa A, Diaz V, Harrison DE, Strong R, Nelson JF, Mozhui K, Auwerx J, Williams EG, Miller RA, Williams RW. Dynamics of genetic and somatic trade-offs in ageing and mortality. Nature. 2026 Jun;654(8118):437-453. doi: 10.1038/s41586-026-10407-9. Epub 2026 Apr 22. PMID: 42020758; PMCID: PMC13253337.

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Matrix Linear Models for Connecting Metabolite Composition to Individual Characteristics