From Candidate Genes to Causal Variants—Strategies for and Examples of Identifying Genes and Sequence Variants in Rodent Populations

Goals of this webinar (candidate genes to causal variants):

  • To understand when it is practical or (just as often) not practical to try to "clone" the gene or nucleotide variant modulating trait variants

  • To understand that defining the crucial causal nucleotide variant is usually a bonus and often not for the translational or even mechanistic utility of discoveries.

  • To review new sequence-based methods to identify common and rare variants—the reduced complexity cross and epoch-effects in reference populations

Presented by:

Dr. Rob Williams
Professor and Chair
Department of Genetics, Genomics, and Informatics
University of Tennessee Health Science Center

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Previous

Identifying genes from QTL using RNA expression and the PhenoGen website (http://phenogen.org)

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Next

Introduction to expression (e)QTL and their role in connecting QTL to genes and molecular networks